ABSTRACT
Objective To study the tumor suppression of Chinese caterpillar fungus water decoction combined cisplatin on a tumor burdened mice .Methods The beforehand vaccinal HCT8 tumor burdened mice were randomly devided into 5 groups(n=10) ,then 3 groups of Chinese caterpillar fungus water decoction were given a tumor burdened mice stomach (2 .5 ,5 .0 ,10 g/kg) ,1 times a day ,12 d .1 group of mice were given saline .1 group were given cisplatin .Determination of different concentrations of cordyceps water decoction lavage ,then observe the changes of tumor‐burdened bone tumors in mice weight .Results For vaccination HCT8 tumor burdened bone tumors had an average weight of each dose group mice compared with saline group have significant difference(P<0 .01) ,while Chinese caterpillar fungus water decoction (2 .5 ,5 .0 g/kg) and cisplatin group mice tumor block is more significant difference(P< 0 .01) ,the tumors had the lighter weight .Conclusion Chinese caterpillar fungus water decoction has tumor suppression effect on tumor burdened mice .
ABSTRACT
AIM:To investigate the role of Shengmai Powder (Radix Ginseng, Radix Ophiopogonis and Fructus schisandrae) (SMP) in treatmen of hemorrhagic shock in rabbits. METHODS: The concentrations of endothelin (ET), tumor necrosis factor (TNF), ? endorphin (? EP) and nitric oxide (NO), the activity of nitric oxide synthase (NOS) in plasma were respectively tested by different biochemical assays in hemorrhagic shock in rabbits. RESULTS: SMP could obviously decrease the ET,TNF,NO level and NOS activity ( P